Editorial Comment to the September 2013 Issue of IMARS Highlights

The first review article of this issue is written by Prof. Kei Fukami. Prof. Fukami at Kurume University School of Medicine, Kurume, Japan, focused on the link between glucagon-like peptide-1 (GLP-1) and AGEs-RAGE axis in diabetic nephropathy. GLP-1 is of current interest as a gut hormone lowering the blood glucose. He summarized the novel beneficial effect of GLP-1 on diabetic nephropathy by lowering the activation of AGEs-RAGE axis.

The second article is a memorial article by Dr. Naoto Koyama at Institute for Innovation, Ajinomoto Co., Inc., a winner of Young Investigator Award of the 22nd Japanese Maillard Reaction Society (JMARS) meeting held on December 21-22 in Tokyo last year. He demonstrated in vitro and in vivo vascular effects (vasodilative activity) of L-Arg-derived AGE, imidazolone such as MG-H1.

Further, this issue includes the article entitled “Dietary advanced glycation end products as an environmental contributor to type 1 diabetes” by Dr. Danielle J Borg at Mater Medical Research Institute, Queensland, Australia. This article focused on the impact of dietary AGEs on development of type 1 diabetes.

From this issue, Dr. Yukio Fujiwara, a new contributing editor, compiles “Papers of Editors’ Choice” in the section of Highlights of the glycation literature. This new effort will give you updated and valuable information.

The IMARS Highlights editors look forward to submission of your articles related to glycation in the field of food and medical sciences as always. Please contact us!

Reiko Inagi, PhD

Division of Nephrology and Endocrinology

The University of Tokyo, Graduate School of Medicine

email: [email protected]

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