Editorial Comment to the July 2017 Issue of IMARS Highlights

IMARS Highlights Vol 12-4_July2017

Editorial comments

This issue specially invited two internationally active researchers in the field of food glycation research, Prof. Monika Pischetsrieder at Friedrich-Alexander Universität Erlangen-Nürnberg, Germany and Prof. Norma Frizzell at University of South Carolina School of Medicine, USA.

Prof. Monika Pischetsrieder focuses on the technical impact of proteomics to evaluate non-enzymatic posttranslational modifications of proteins by Maillard reaction in processed food and summarizes future perspective of achievement of qualitative and quantitative non-targeted proteomic analysis. Such technical progress will give us new insight to understand protein damage by Maillard reaction during food processing.

Prof. Norma Frizzell and her colleagues highlight the pathophysiological effect of fumarate-induced succination in a variety of conditions associated with mitochondrial dysfunction, leading to induction of mitochondrial stress as well as endoplasmic reticulum stress. They update the mechanism how various kinds of succinated proteins induce different pathophysiological effects in different cells or organs.

I deeply thank their great contributions to the IMARS Highlights. The IMARS Highlights editors always look forward to submission of your articles, comments to any kinds of issues published in IMARS Highlights and other glycation-related issues in the field of food and medical sciences.

Reiko Inagi, PhD

Division of Chronic Kidney Disease Pathophysiology
The University of Tokyo Graduate School of Medicine
email: [email protected]

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