In this issue, I invited Drs. Tingfu Liang and Jin Tatsuzaki at Tokiwa Phytochemical Co. Ltd., Japan to write articles in the IMARS Highlights. They summarized the impact and significance of anti-glycation activity of the plant extract of Kaempferia parviflora (SIRTMAX®), which belongs to Zingiberaceae family and is indigenous to South Asia, including Thailand and Laos, in animal experiments and human trials. Interestingly, the SIRTMAX® as well as the compounds isolated form the SIRTMAX® effectively stimulated the activity of sirtuin 1 (SIRT1), which closely links to longevity, suggesting the anti-aging effects of SIRTMAX® via suppression of glycative stress for productive aging.
This issue also includes two special articles written by the winners of Young Investigator Award (poster presentation) of the 12th ISMR, Dr. Ghada Elmhiri (food science) and Dr. Emiko Sato (medical science) as continued from the last issue.
Dr. Ghada Elmhiri at Institut Polytechnique, France, received the award on “Formula milk derived CML induces RAGE activation, long term inflammation and oxidative stress in IUGR piglets”. Dr. Emiko Sato at Tohoku University Graduate School of Medicine, Japan, got the award on “Carbonyl stress and inappropriate renal renin angiotensin system activity associate with blood pressure elevation”. These young and active researchers will open a new avenue to advance science on the Maillard reaction and its biological significance.
I deeply thank their great contributions to the IMARS Highlights. The IMARS Highlights editors always look forward to submission of your articles, comments to any kinds of issues published in IMARS Highlights and other glycation-related issues in the field of food and medical sciences.
Reiko Inagi, PhD
Division of Chronic Kidney Disease Pathophysiology,
The University of Tokyo Graduate School of Medicine
email: [email protected]